Toxoplasma gondii: 25 years and 25 major advances for the field.
نویسنده
چکیده
This article is an attempt to identify the most significant highlights of Toxoplasma research over the last 25 years. It has been a period of enormous progress and the top 25 most significant advances, in the view of this author, are described. These range from the bench to the bedside and represent a tremendous body of work from countless investigators. And, having laid out so much that has been discovered, it is impossible not to also reflect on the challenges that lie ahead. These, too, are briefly discussed. Finally, while every effort has been made to view the field as a whole, the molecular biology background of the author almost certainly will have skewed the relative importance attached to past and future advances. Despite this, it is hoped that the reader will agree with, or at least not disagree too strongly with, most of the choices presented here.
منابع مشابه
Cloning and sequencing of Toxoplasma gondii major surface antigen (SAG1) gene
Genetic typing methods of T. gondii strains have been extensively perfected in recent years. From a technical point of view, many tools usable for genetic studied on single-copy loci have been used: RFLP, PCR-RFLP, sequencing, RAPD-PCR and isoenzyme analysis. We described the cloning and sequence analysis of the gene which encodes the major surface antigen (SAG1 or P30) of T. gondii. SAG1 is ...
متن کاملToxoplasma gondii infection in slaughtered ewes in Khorramabad, west of Iran: A preliminary molecular study
BACKGROUND: The parasitic protozoa Toxoplasma gondii is widely prevalent in humans and warm-blooded animals. Humans are usually infected with T. gondii by ingesting oocysts shed by cats or by ingesting viable tissue cysts present in raw or undercooked meat. OBJECTIVES: This preliminary study was conducted to assess the frequency of Toxoplasma gondii infection in tissue samples of ewes slaughter...
متن کاملSeroprevalence of Toxoplasma gondii and Vitamin D3 Concentration among School Children 7-18 Years Old in Bojnurd City
Introduction: Toxoplasma gondii is a protozoan parasite with relatively high prevalence in human societies. Due to the lack of information on toxoplasmosis infection in school-aged children in Bojnord, the present study aimed to assess the prevalence of toxoplasmosis in school-age students and the level of vitamin D3 deficiency in them in Bojnurd, Northeast of Iran. Method: In this cross-secti...
متن کاملSerological Evaluation of Experimental Toxoplasma gondii Infection in Cats by Using Immunoblotting Based on an Affinity Purified Surface Antigen
Toxoplasma gondii is an apicomplexan parasite that infects human and almost all warm-blooded animals. The life cycle of the parasite includes an asexual reproduction in intermediate hosts (Mammals and birds) and a sexual reproduction in definitive hosts (Felidae). Cats are both the intermediate and the definitive host for T. gondii. The aim of this study was to investigate anti-T. gondii antibo...
متن کاملToxoplasma gondii Infection in Free-Ranged (FR) and Caged Chickens and Turkey by Bioassay and Serologic Methods in Hamadan, Iran
Introduction: Toxoplasmosis is a widely prevalent zoonotic disease, caused by T. gondii. Chickens, consumed widely in many countries, are considered as one of the most important hosts in the epidemiology of T. gondii infection because they could be a main source of infection for both cats and humans. There was no information regarding T. gondii infection in chickens in this area, therefore, thi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- International journal for parasitology
دوره 39 8 شماره
صفحات -
تاریخ انتشار 2009